Abstract The purpose of this study is to compare the effects of the different physical factors on lipoproteins accumulation in the aorta artery. Results revealed that hemodynamic parameters (WSS, OSI, RRT) together affect spatial distributions of lipoproteins concentration in the human aorta. Moreover, decreasing the frequency of pulsatile flow and particle size leads to more lipoproteins accumulated on the luminal surface. In addition, given the same flow rate, the pulsatile flow could reduce lipoproteins concentration in the luminal surface of aorta relative to a steady flow condition. The present computer strategy may have great potential in predicting the local atherosclerosis lesion.

中文翻译：

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沃默斯利数和粒子半径对人主动脉中脂蛋白积累的影响

摘要 本研究的目的是比较不同物理因素对主动脉内脂蛋白积累的影响。结果表明，血流动力学参数（WSS、OSI、RRT）共同影响人主动脉中脂蛋白浓度的空间分布。此外，降低脉动流的频率和粒径会导致更多的脂蛋白积聚在管腔表面。此外，在相同的流速下，相对于稳定的流动条件，脉动流可以降低主动脉腔表面的脂蛋白浓度。目前的计算机策略在预测局部动脉粥样硬化病变方面可能具有很大的潜力。