Current elastography techniques are limited in application to accurately assess spatially resolved corneal elasticity in vivo for human eyes. The air‐puff optical coherence elastography (OCE) with an eye motion artifacts correction algorithm is developed to distinguish the in vivo cornea vibration from the eye motion and visualize the Lamb wave propagation clearly in healthy subjects. Based on the Lamb wave model, the phase velocity dispersion curve in the high‐frequency is calculated to obtain spatially resolved corneal elasticity accurately with high repeatability. It is found that the corneal elasticity has regional variations and is correlated with intraocular pressure, which suggests that the method has the potential to provide noninvasive measurement of spatially resolved corneal elasticity in clinical practice.

中文翻译：

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使用 Lamb 波光学相干弹性成像对人眼空间分辨角膜弹性进行体内无创测量。

目前的弹性成像技术在准确评估人眼体内空间分辨角膜弹性方面的应用受到限制。开发了带有眼球运动伪影校正算法的吹气光学相干弹性成像 (OCE) 以区分体内角膜振动和眼球运动，并清楚地显示 Lamb 波在健康受试者中的传播。基于Lamb波模型，计算高频中的相速度色散曲线，准确获得空间分辨的角膜弹性，重复性好。发现角膜弹性具有区域差异，并与眼压相关，这表明该方法有可能在临床实践中提供空间分辨角膜弹性的无创测量。