Leishmaniasis is an important infectious disease that develops because of escaping parasite from the host immune system or preventing host macrophages apoptosis. Recently, the development of transgenic methods and the manipulation of the parasite genome has provided many advantages. So, in this study, the effect of the transgenic Leishmania infantum expressing mLLO‐BAX‐SMAC proteins was examined in accelerating host cell apoptosis.

中文翻译：

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在体外和体内评价表达mLLO-BAX-SMAC的转基因利什曼原虫在感染巨噬细胞凋亡中的作用。

利什曼病是一种重要的传染病，由于寄生虫从宿主免疫系统逃逸或阻止宿主巨噬细胞凋亡而发展。近来，转基因方法的发展和寄生虫基因组的操纵提供了许多优点。因此，在这项研究中，研究了表达mLLO‐BAX‐SMAC蛋白的转基因婴儿利什曼原虫在促进宿主细胞凋亡中的作用。