Identifying the mechanisms that govern the precise sequence of tissue deformations and flows during development is a major topic in developmental biology. Recent studies have explored how the deformation or the flow of a tissue region can be induced by the activity of a neighboring region through mechanical coupling. Such a coupling process is akin to chemical induction, whereby differentiation in a region of competent cells is stimulated by a neighboring region through chemical induction: we therefore propose to name this phenomenon 'mechanical induction'. Focusing on examples of mechanically induced epithelial flow or planar deformation in vivo, this review aims at discussing the processes driving mechanical induction and the competence factors modulating the induced morphogenesis, in order to highlight the importance of integrating tissue and inter-tissue scales to understand morphogenesis.

中文翻译：

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机械诱导和上皮形态发生能力。

识别控制发育过程中组织变形和流动的精确顺序的机制是发育生物学的一个主要主题。最近的研究已经探索了如何通过机械耦合通过邻近区域的活动来诱导组织区域的变形或流动。这样的偶联过程类似于化学诱导，由此感受态细胞区域中的分化通过化学诱导被邻近区域刺激：因此，我们建议将该现象命名为“机械诱导”。本文以体内机械诱导的上皮流动或平面变形为例，旨在探讨驱动机械诱导的过程以及调节诱导的形态发生的能力因子，