The kinetochore is at the heart of chromosome segregation in mitosis and meiosis. Rather than a static linker complex for chromatin and spindle microtubules, it is highly dynamic in composition, size, and shape. While known for decades that it can expand and grow a fibrous meshwork known as the corona, it was until recently unclear what constitutes this ‘crown’ and what its relevance is for kinetochore function. Here, we highlight recent discoveries in fibrous corona biology, and place them in the context of the processes that orchestrate high-fidelity chromosome segregation.

中文翻译：

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着丝粒冠冕：染色体分离中的纤维状电晕。

线粒体是有丝分裂和减数分裂中染色体分离的核心。它不是染色质和纺锤体微管的静态连接子复合物，而是在组成，大小和形状方面具有高度动态性。尽管几十年来人们已经知道它可以扩张和生长被称为电晕的纤维网，但直到最近还不清楚这种“冠”的构成以及与动粒功能的相关性。在这里，我们重点介绍了纤维电晕生物学的最新发现，并将其置于协调高保真染色体分离的过程的背景下。