In Reply We thank Nagel et al for their thoughtful comments on our article on medical management vs mechanical thrombectomy (MT) for mild strokes.¹ We agree that medically treated patients with large vessel occlusion (LVO) with mild deficits can potentially experience neurological deterioration and rescue therapy may be required. We do not know how often this occurs or if there are factors that might increase or decrease this rate.

中文翻译：

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意图治疗原则答复的重要性。

在答复中，我们感谢Nagel等人对我们关于轻度卒中的医疗管理与机械血栓切除术（MT）的文章的体贴评论。¹我们同意，药物治疗的大血管闭塞（LVO）伴轻度虚弱的患者可能会出现神经功能恶化，可能需要进行抢救治疗。我们不知道这种情况发生的频率，也不知道是否有可能增加或减少该比率的因素。