Each internal organ may perform many different functions under central regulation, yet how these processes are coordinated is poorly understood. The last three decades have witnessed a renaissance in tract tracing with genetically engineered strains of viruses that rapidly interrogate viscera-specific projections in the CNS. The application of novel methods to study cell type-specific projections through trans-synaptically transmitted virus 'label' highlights projections exclusively originating from neurons expressing a very specific molecular phenotype. This has opened the door to neuroanatomical studies interrogating organ-specific projections in the CNS at an unprecedented scale. In this contribution to the Special Issue we present an overview of the present state and of future opportunities in charting viscera-brain specific connectivity and in linking brain circuits to internal organ function.

中文翻译：

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病毒用于询问中枢神经系统内脏特定投射的用途。

每个内部器官可以在中央监管下执行许多不同的功能，但是如何协调这些过程却知之甚少。在过去的三十年中，使用遗传工程病毒株快速追踪中枢神经系统内脏特定投射的病毒在风道追踪中得到了复兴。通过反突触传递的病毒“标记”研究新的细胞类型特异性预测的新方法的应用突出了仅源自表达非常特定的分子表型的神经元的预测。这为神经解剖学研究打开了大门，以前所未有的规模询问中枢神经系统中器官特定的预测。