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A search for the physical basis of the genetic code.
Biosystems ( IF 1.6 ) Pub Date : 2020-05-04 , DOI: 10.1016/j.biosystems.2020.104148
S Arbabi Moghadam 1 , M Klobukowski 2 , J A Tuszynski 3
Affiliation  

DNA contains the genetic code, which provides complete information about the synthesis of proteins in every living cell. Each gene encodes for a corresponding protein but most of the DNA sequence is non-coding. In addition to this non-coding part of the DNA, there is another redundancy, namely a multiplicity of DNA triplets (codons) corresponding to code for a given amino acid. In this paper we investigate possible physical reasons for the coding redundancy, by exploring free energy considerations and abundance probabilities as potential insights.



中文翻译:

寻找遗传密码的物理基础。

DNA包含遗传密码,该密码提供有关每个活细胞中蛋白质合成的完整信息。每个基因编码一个相应的蛋白质,但是大多数DNA序列是非编码的。除了DNA的这个非编码部分外,还有另一个冗余,即对应于给定氨基酸编码的多个DNA三联体(密码子)。在本文中,我们通过探索自由能的考虑因素和丰度概率作为潜在的见解,研究了编码冗余的可能物理原因。

更新日期:2020-05-04
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