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Couples experiences of receiving uncertain results following prenatal microarray or exome sequencing: A mixed-methods systematic review.
Prenatal Diagnosis ( IF 3 ) Pub Date : 2020-05-02 , DOI: 10.1002/pd.5729
Eleanor Harding 1, 2 , Jennifer Hammond 2, 3 , Lyn S Chitty 2, 3 , Melissa Hill 2, 3 , Celine Lewis 2, 3
Affiliation  

Tests in pregnancy such as chromosomal microarray analysis and exome sequencing are increasing diagnostic yield for fetal structural anomalies, but have greater potential to result in uncertain findings. This systematic review investigated the experiences of prospective parents about receiving uncertain results from these tests.

中文翻译:

夫妻在产前微阵列或外显子组测序后收到不确定结果的经历:混合方法系统评价。

妊娠期检测(例如染色体微阵列分析和外显子组测序)正在提高胎儿结构异常的诊断率,但更有可能导致不确定的结果。本系统评价调查了准父母从这些测试中收到不确定结果的经历。
更新日期:2020-05-02
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