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Association between glioblastoma cell-derived vessels and poor prognosis of the patients.
Cancer Communications ( IF 16.2 ) Pub Date : 2020-05-02 , DOI: 10.1002/cac2.12026
Xin Mei 1, 2 , Yin-Sheng Chen 1 , Qing-Ping Zhang 3 , Fu-Rong Chen 1 , Shao-Yan Xi 1 , Ya-Kang Long 4 , Ji Zhang 1 , Hai-Ping Cai 1 , Chao Ke 1 , Jing Wang 1 , Zhong-Ping Chen 1
Affiliation  

Vessels with different microcirculation patterns are required for glioblastoma (GBM) growth. However, details of the microcirculation patterns in GBM remain unclear. Here, we examined the microcirculation patterns of GBM and analyzed their roles in patient prognosis together with two well‐known GMB prognosis factors (O6‐methylguanine DNA methyltransferase [MGMT] promoter methylation status and isocitrate dehydrogenase [IDH] mutations).

中文翻译:

胶质母细胞瘤细胞来源的血管与患者预后不良之间的关联。

胶质母细胞瘤(GBM)的生长需要具有不同微循环模式的血管。但是,GBM中微循环模式的细节仍不清楚。在这里,我们检查了GBM的微循环模式,并分析了它们在患者预后中的作用以及两个著名的GMB预后因素(O 6-甲基鸟嘌呤DNA甲基转移酶[MGMT]启动子甲基化状态和异柠檬酸脱氢酶[IDH]突变)。
更新日期:2020-05-02
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