4,4’-Dithiobisbenzoic acid (DTBA) is equivalent to two 4-mercaptobenzoic acid (pMBA) molecules connected together after losing H⁺, and this bimolecular mechanism of DTBA efficiently promotes the ionization reaction. Under the irradiation of laser light, DTBA molecules are broken to form bimolecules similar to pMBA, and this kind of bimolecular coupling greatly increases the probability of binding with Ag NPs. Also, this molecule has the carboxylic acid group, which leads to a certain sensitivity to pH. In this article, through the comparison of DTBA and pMBA parallel experiments, it is clear that DTBA has better Raman activity, higher reaction efficiency, and more stable reaction than pMBA. The occurrence of this highly efficient ionization reaction under the monitoring of surface-enhanced Raman spectroscopy (SERS) provides a certain value for the progress of further related reactions, and it also has a wide range of applications in pH sensors and intracellular pH monitoring.

The study of efficient ionization reaction of 4,4’-dithiobisbenzoic acid with bimolecular structure

中文翻译：

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表面等离子催化作用实现DTBA的高效电离反应

4,4'-二硫代双苯甲酸（DTBA）相当于失去H ⁺后连接在一起的两个4-巯基苯甲酸（pMBA）分子，并且DTBA的这种双分子机制有效地促进了电离反应。在激光的照射下，DTBA分子断裂形成类似于pMBA的双分子，这种双分子偶联极大地增加了与Ag NP结合的可能性。而且，该分子具有羧酸基，这导致对pH的一定敏感性。在本文中，通过比较DTBA和pMBA平行实验，很明显DTBA比pMBA具有更好的拉曼活性，更高的反应效率和更稳定的反应。在表面增强拉曼光谱（SERS）的监测下，这种高效电离反应的发生为进一步的相关反应的进展提供了一定的价值，

具有双分子结构的4,4'-二硫代双苯甲酸的有效电离反应的研究