As COVID-19 spreads through the world, most cases to date are in middle- and high-income nations. The impact on resource-poor nations remains unknown. Amongst many factors likely to affect the impact of COVID-19 in these areas, co-infections need to be considered. Here, we discuss whether the immunomodulatory effects of helminth infections may affect COVID-19 severity. Helminth co-infections can skew systemic immunity towards type 2 responses. Here, Bradbury and colleagues consider how this may impact the severity of COVID-19 in helminth-endemic regions.

中文翻译：

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蠕虫共感染会改变流行地区的COVID-19严重程度吗？

随着COVID-19在世界范围内的传播，迄今为止，大多数病例都发生在中等收入和高收入国家。对资源匮乏国家的影响仍然未知。在可能影响COVID-19在这些地区的影响的众多因素中，需要考虑合并感染。在这里，我们讨论蠕虫感染的免疫调节作用是否会影响COVID-19严重程度。蠕虫合并感染可使全身免疫力偏向2型反应。在这里，布拉德伯里（Bradbury）及其同事考虑了这可能如何影响蠕虫流行地区COVID-19的严重程度。