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Adenosine kinase inhibition enhances microvascular dilator function and improves left ventricle diastolic dysfunction.
Microcirculation ( IF 2.4 ) Pub Date : 2020-04-30 , DOI: 10.1111/micc.12624
Alec Davila 1 , Yanna Tian 1 , Istvan Czikora 1 , Amanda S Weissman 1 , Nicholas Weinand 1 , Guangkuo Dong 2 , Jiean Xu 3 , Jie Li 3 , Huabo Su 3 , Gaston Kapuku 4 , Yuqing Huo 3 , Zsolt Bagi 1
Affiliation  

Inhibition of adenosine kinase (ADK), via augmenting endogenous adenosine levels exerts cardiovascular protection. We tested the hypothesis that ADK inhibition improves microvascular dilator and left ventricle (LV) contractile function under metabolic or hemodynamic stress.

中文翻译:

腺苷激酶抑制增强微血管扩张器功能并改善左心室舒张功能障碍。

抑制腺苷激酶 (ADK),通过增加内源性腺苷水平发挥心血管保护作用。我们测试了在代谢或血液动力学压力下 ADK 抑制改善微血管扩张器和左心室 (LV) 收缩功能的假设。
更新日期:2020-04-30
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