Mental disorders are ranked among the most substantial causes of disability worldwide. Moreover, they are increasingly being recognized as complex diagnostic entities with largely unknown etiological backgrounds. Apart from genetic risk factors, several environmental exposures, including pregnancy and perinatal risk factors, psychosocial stressors, urbanicity, poverty and substance use, have been associated with susceptibility to mood disorders and schizophrenia. It is also of great importance that severe mental disorders are associated with reduced life expectancy, mostly due to cardiovascular comorbidities. At this point, it should be noted that the exact mechanisms underlying causal inferences between certain environmental factors, e.g. urbanicity or seasonality, and the risk of mental disorders are yet to be determined.

中文翻译：

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空气污染与心理健康：推动这一领域向前发展。

精神障碍被列为全球最严重的残疾原因之一。此外，它们被越来越多地认为是病因背景未知的复杂诊断实体。除遗传风险因素外，还包括妊娠和围产期风险因素，社会心理压力源，城市化，贫困和吸毒等多种环境暴露，它们与情绪障碍和精神分裂症的易感性有关。同样重要的是，严重的精神障碍与预期寿命缩短有关，这主要是由于心血管合并症引起的。在这一点上，应该指出，某些环境因素（例如城市性或季节性）与精神障碍风险之间因果关系推断的确切机制尚待确定。