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The vestibulo-masseteric reflex and the acoustic-masseteric reflex: a reliability and responsiveness study in healthy subjects.
Experimental Brain Research ( IF 2 ) Pub Date : 2020-04-13 , DOI: 10.1007/s00221-020-05804-z
Nicola Loi 1 , Andrea Manca 1 , Francesca Ginatempo 1 , Franca Deriu 1
Affiliation  

The vestibulo-masseteric reflex (VMR or p11 wave), the acoustic-masseteric reflex (AMR or p1/n21 wave) and the mixed vestibulo-cochlear p11/n21 potential are responses of masseter muscles to sound that can be employed to evaluate brainstem function. This study was aimed at establishing the test–retest reliability and responsiveness of these reflex parameters according to the type of electrode configuration. Twenty-two healthy volunteers (M:F = 11:11; mean age 25.3 ± 5.2 years) participated in two testing sessions separated by one week. Zygomatic and mandibular montages were compared following unilateral and bilateral stimulations. For reliability purposes, intraclass correlation coefficient (ICC), coefficient of variation of the method error (CVME) and standard error of measurement (SEM) were calculated. The minimal detectable difference (MDD) was also determined as a measure of responsiveness. Both VMR (p11 wave) and AMR could be consistently evoked from test to retest, although the frequency rate was significantly higher (all p values ≤ 0.009) with zygomatic (VMR: 97.7–100%; AMR: 86.9–97.6%) than mandibular montage (VMR: 84.7–89.8%; AMR: 65.0–67.8%), with no significant differences between unilateral and bilateral stimulations. Good-to-excellent reliability and responsiveness (high ICC, low CVME, SEM and MDD scores) were detected for corrected amplitudes and peak latencies for all reflex responses, whereas raw amplitudes were associated to poor reliability. The reliability of the zygomatic montage proved superior to the mandibular montage for all reflex responses. Given their high test–retest consistency and capability to study different features of the reflex arch, both peak latencies and corrected amplitudes should be reported and considered in the interpretation of reflex testing results.



中文翻译:

前庭反射和听觉反射:健康受试者的可靠性和反应性研究。

前庭-肌肉反射(VMR或p11波),声学-身体反射(AMR或p1 / n21波)和前庭-耳蜗混合p11 / n21电位是咬肌对声音的反应,可用于评估脑干功能。这项研究旨在根据电极配置的类型建立这些反射参数的重测信度和响应度。22名健康志愿者(男:女= 11:11;平均年龄25.3±5.2岁)参加了两次测试,每次间隔一周。比较单侧和双侧刺激后的y骨和下颌蒙太奇。出于可靠性目的,计算了组内相关系数(ICC),方法误差的变异系数(CVME)和测量的标准误差(SEM)。还确定了最小可检测差异(MDD)作为响应度的量度。从测试到重新测试,VMR(p11波)和AMR都可以被一致地诱发,尽管频率率明显更高(所有p值≤0.009)骨(VMR:97.7–100%; AMR:86.9–97.6%)比下颌蒙太奇(VMR:84.7–89.8%; AMR:65.0–67.8%),单侧和双侧刺激之间无显着差异。对于所有反射响应,校正振幅和峰潜伏期均检测到了良好至优异的可靠性和响应能力(高ICC,低CV ME,SEM和MDD分数),而原始振幅则与较差的可靠性相关。在所有反射反应中,go骨剪辑的可靠性均优于下颌剪辑。由于它们具有很高的重测一致性,并且能够研究反射弓的不同特征,因此在报告反射测试结果时应报告并考虑峰值潜伏期和校正幅度。

更新日期:2020-04-13
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