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Circular Tessera Codes in the Evolution of the Genetic Code
Bulletin of Mathematical Biology ( IF 3.5 ) Pub Date : 2020-04-01 , DOI: 10.1007/s11538-020-00724-z
Elena Fimmel 1 , Martin Starman 1 , Lutz Strüngmann 1
Affiliation  

The origin of the modern genetic code and the mechanisms that have contributed to its present form raise many questions. The main goal of this work is to test two hypotheses concerning the development of the genetic code for their compatibility and complementarity and see if they could benefit from each other. On the one hand, Gonzalez, Giannerini and Rosa developed a theory, based on four-based codons, which they called tesserae. This theory can explain the degeneracy of the modern vertebrate mitochondrial code. On the other hand, in the 1990s, so-called circular codes were discovered in nature, which seem to ensure the maintenance of a correct reading-frame during the translation process. It turns out that the two concepts not only do not contradict each other, but on the contrary complement and enrichen each other.

中文翻译:

遗传密码演变中的循环 Tessera 密码

现代遗传密码的起源和促成其目前形式的机制提出了许多问题。这项工作的主要目标是检验关于遗传密码发展的两个假设的兼容性和互补性,看看它们是否可以相互受益。一方面,Gonzalez、Giannerini 和 Rosa 提出了一种基于四基密码子的理论,他们称之为 tesserae。这一理论可以解释现代脊椎动物线粒体密码的退化。另一方面,在 1990 年代,在自然界中发现了所谓的循环代码,这似乎可以确保在翻译过程中保持正确的阅读框架。事实证明,这两个概念不仅不相互矛盾,反而相互补充和丰富。
更新日期:2020-04-01
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