Abstract The high-resolution imaging of alpha particles is required for the development of radio-compounds for targeted alpha-particle therapy or alpha emitter detection at nuclear facilities. Therefore, we developed an ultrahigh-resolution, real-time alpha-particle imaging system for observing the trajectories of alpha particles in a scintillator. The developed alpha-particle imaging system is made from a 1-μm-diameter fiber-structure scintillator plate that is optically coupled with the first of two sequentially connected tapered optical fiber plates. The output of the second, larger tapered optical fiber plate was imaged by an electron-multiplied (EM) cooled CCD camera. With our developed imaging system, we observed images of alpha particles having a spatial resolution of ~11 μm. We could also observe the trajectories of alpha particles with Bragg peaks for the angled incident alpha particles. We conclude that this imaging system, which can observe the trajectory of alpha particles in a fiber-structure scintillator, is promising for research on targeted alpha-particle therapy or alpha emitter detection at nuclear facilities.

中文翻译：

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超高分辨率辐射实时成像系统的开发，用于观察闪烁体中阿尔法粒子的轨迹

摘要 α 粒子的高分辨率成像是开发用于在核设施中进行靶向 α 粒子治疗或 α 发射器检测的放射性化合物的必要条件。因此，我们开发了一种超高分辨率、实时 alpha 粒子成像系统，用于观察闪烁体中 alpha 粒子的轨迹。开发的 α 粒子成像系统由直径为 1 微米的光纤结构闪烁体板制成，该闪烁体板与两个顺序连接的锥形光纤板中的第一个进行光学耦合。第二个较大的锥形光纤板的输出由电子倍增 (EM) 冷却 CCD 相机成像。使用我们开发的成像系统，我们观察到空间分辨率约为 11 μm 的 alpha 粒子图像。我们还可以观察到具有布拉格峰的 alpha 粒子的轨迹，用于倾斜入射的 alpha 粒子。我们得出结论，该成像系统可以观察纤维结构闪烁体中 α 粒子的轨迹，有望用于研究核设施中的靶向 α 粒子治疗或 α 发射器检测。