Veterinary Anaesthesia and Analgesia ( IF 1.7 ) Pub Date : 2020-02-26 , DOI: 10.1016/j.vaa.2020.02.003 Teppei Kanda 1 , Yutaro Oishi 2 , Ayumu Kajiyama 2 , Yuki Shimizu 1 , Noritaka Maeta 1 , Kayo Furumoto 1 , Toshinori Furukawa 3
Objective
To investigate the effects of a heat and moisture exchanger (HME) on the temperature and humidity of inhaled gas in isoflurane-anesthetized dogs.
Study design
Prospective, interventional study.
Animals
A total of four experimental dogs and four client-owned dogs weighing 13.9 ± 7.4 kg (mean ± standard deviation).
Methods
The four experimental dogs were anesthetized on two occasions with and without an intact HME at least 1 week apart. The four client-owned dogs were anesthetized once only for a surgical procedure and assigned to the HME group or no-HME group in alternate order, resulting in six dogs for each group. All dogs were premedicated, anesthetized with propofol and intubated. The HME was connected to the endotracheal tube. Anesthesia was maintained with isoflurane. A digital thermo-hygrometer was placed between the endotracheal tube and HME. The temperature and relative humidity of the inhaled gas were measured every 5 minutes for 60 minutes and the absolute humidity was calculated at each time point.
Results
The temperature and absolute humidity of the inhaled gas was significantly higher at 5–60 minutes after intubation in the HME group than in the no-HME group. Absolute humidity was maintained above 29 mg H2O L−1 in the HME group. No significant time-dependent effects on temperature, relative humidity or absolute humidity of the inhaled gas were observed.
Conclusions and clinical relevance
The temperature and absolute humidity of the inhaled gas were higher when an HME was used during isoflurane anesthesia in dogs. The use of an HME may reduce the risk of dehydration and dysfunction of the airway mucosal epithelium.
中文翻译:
湿热交换剂对异氟烷麻醉犬中吸入气体的温度和湿度的影响。
目的
研究热湿交换器(HME)对异氟烷麻醉犬中吸入气体的温度和湿度的影响。
学习规划
前瞻性干预研究。
动物
总共四只实验犬和四只客户拥有的犬重13.9±7.4公斤(平均±标准偏差)。
方法
在有和没有完整HME的情况下,至少相隔1周对这四只实验犬进行两次麻醉。仅对四只客户拥有的狗进行一次外科手术麻醉,然后以交替顺序将其分配到HME组或非HME组,每组产生六只狗。所有的狗都进行了药物治疗,用异丙酚麻醉并插管。HME连接到气管导管。用异氟烷维持麻醉。将数字温湿度计放置在气管导管和HME之间。每5分钟测量一次吸入气体的温度和相对湿度,持续60分钟,并在每个时间点计算绝对湿度。
结果
HME组在插管后5–60分钟时吸入气体的温度和绝对湿度显着高于非HME组。HME组的绝对湿度保持在29 mg H 2 O L -1以上。没有观察到对吸入气体的温度,相对湿度或绝对湿度有明显的时间依赖性影响。
结论与临床意义
在犬的异氟烷麻醉期间使用HME时,吸入气体的温度和绝对湿度较高。使用HME可以减少脱水和气道粘膜上皮功能障碍的风险。