The homogenously rhodium‐catalyzed reductive amination of 1‐undecanal was performed in two different thermomorphic solvent systems with the ligand Xantphos. The influences of partial pressure, temperature, methanol and catalyst concentration on the reaction were investigated. Based on a network analysis a kinetic model was derived and successfully parametrized for all studied solvent systems. Simulation results were found to be in good agreement with the experiments and allow a further process development and optimization.

中文翻译：

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铑催化不同溶剂体系十一烷的还原胺化动力学模型

在带有配体Xantphos的两种不同的热定型溶剂体系中，均进行了铑的1-十一烷的均相铑还原胺化反应。研究了分压，温度，甲醇和催化剂浓度对反应的影响。基于网络分析，得出了动力学模型，并成功地对所有研究的溶剂系统进行了参数化。仿真结果与实验结果非常吻合，可以进行进一步的工艺开发和优化。