ABSTRACT Although dental practitioners orthodontically move teeth on a daily basis, questions persist regarding the complex biological mechanisms involved. The importance of knowledge about the mechanobiology of tooth movement is ever-increasing as orthodontics is undergoing a shift from a focus on ‘biomechanics’ to ‘biology’. As in other areas of healthcare, practitioners aspire to provide individualised treatment, as well as potentially accelerate tooth movement and attenuate adverse effects. In vitro and in vivo models of tooth movement research, including those which have been conducted in New Zealand, will be described, with a vision toward future directions.

中文翻译：

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调查正畸牙齿移动：挑战和未来方向

摘要 尽管牙医每天都要进行牙齿正畸，但有关所涉及的复杂生物学机制的问题仍然存在。随着正畸正从关注“生物力学”向“生物学”转变，有关牙齿运动力学生物学知识的重要性与日俱增。与医疗保健的其他领域一样，从业者渴望提供个性化的治疗，并有可能加速牙齿移动并减轻不良反应。将描述牙齿运动研究的体外和体内模型，包括在新西兰进行的那些模型，并展望未来的方向。