The anti-inflammatory activity of benzopyran derivatives extracted from the Myagropsis myagroides against lipopolysaccharide (LPS)-induced RAW 264.7 murine macrophage cell line was examined. The three constituents of M. myagroides extracts were identified as the sargachromanol G, sargachromanol I, and saringosterol by ¹H and ¹³C NMR. Sargachromanol G, sargachromanol I, and saringosterol at concentrations of 50 μg/mL showed inhibitory effects on LPS induced interleukin-6 production (by 84%, 90%, and 96%, respectively) and tumor necrosis factor (by 74%, 82%, and 98%, respectively). These results confirm the potential anti-inflammatory effects of sarga-chromanol G, sargachromanol I, and saringosterol.

检查了从Myagropsis myagroides提取的苯并吡喃衍生物对脂多糖（LPS）诱导的RAW 264.7鼠巨噬细胞系的抗炎活性。通过¹ H和¹³ C NMR鉴定出Myagroides提取物的三个成分为sargachromanol G，sargachromanol I和saringosterol 。浓度为50μg/ mL的Sargachromanol G，sargachromanol I和saringosterol对LPS诱导的白介素6产生（分别为84％，90％和96％）和肿瘤坏死因子（分别为74％，82％）具有抑制作用，和分别为98％）。这些结果证实了sarga-chromanol G，sargachromanol I和saringosterol的潜在抗炎作用。