Amoxicillin (AMX) is one of the most widely used antibiotic drugs, which plays an effective role in eliminating bacterial and fungal diseases. However, on account of its poor biodegradability, AMX often leads to water pollution. In this study, the AMX in water was oxidized by atmospheric-pressure air microplasma (APAM). The degradation pathway of AMX in aqueous solution was studied at the molecular level by high-performance liquid chromatography–tandem mass spectrometry (HPLC-MS). The results show that AMX can be rapidly removed by APAM. Meanwhile, eight intermediate and two final degradation products were detected. The reactivity of the AMX with different active species generated by APAM can be described in the following sequence: hydroxyl radical ( $\cdot $ OH) > hydrogen peroxide (H₂O₂) > ozone(O₃). The APAM treatment is a promising way to oxidize AMX in the aqueous solution into CO, CO₂, and H₂O.

中文翻译：

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常压空气微等离子体处理水中阿莫西林的降解机理

阿莫西林（AMX）是应用最广泛的抗生素药物之一，在消除细菌和真菌疾病方面发挥着有效作用。然而，由于其生物降解性差，AMX经常导致水污染。在这项研究中，水中的 AMX 被常压空气微等离子体 (APAM) 氧化。通过高效液相色谱-串联质谱 (HPLC-MS) 在分子水平上研究了 AMX 在水溶液中的降解途径。结果表明，APAM 可以快速去除 AMX。同时，检测到八种中间产物和两种最终降解产物。AMX与APAM产生的不同活性物质的反应性可以用以下顺序描述：羟基自由基（ $\cdot $ OH) > 过氧化氢 (H ₂ O ₂ ) > 臭氧(O ₃ )。APAM 处理是将水溶液中的 AMX 氧化成 CO、CO ₂和 H ₂ O 的一种很有前景的方法。