Ethyl formate (EF) is becoming an insecticide of choice for protecting stored commodities. Along with EF, methyl salicylate (MS) is also naturally occurring, and both are generally regarded as safe fumigants for their higher threshold limit values (TLV) and residual status below minimum residue limit (MRL). Sub-lethal doses of EF and MS were evaluated to determine if there was a synergistic effect on fumigation against life stages of the adzuki bean beetle, Callosobruchus chinensis (L.) infesting adzuki bean grains. Based on lethal dose (LD) values, the C. chinensis eggs and adults were equally susceptible to EF followed by larvae and pupae. Adults were the most MS-sensitive followed by eggs and larvae, and pupae were the most tolerant stage. The mortalities of all the life stages of C. chinensis by combined fumigation with sub-lethal EF and MS doses were significantly higher compared to the sum of their separate fumigations revealing a notable synergistic effect. Moreover, the maximum doses of EF and MS tested for synergistic fumigation test did not hamper the germination potential of adzuki been seeds. The synergistic effect between EF and MS can significantly reduce the dose rate of flammable EF against C. chinensis thereby offering a good prospect for EF + MS formulation as an alternative to safeguard stored adzuki bean.

甲酸乙酯（EF）成为保护储存商品的首选杀虫剂。与EF一起，水杨酸甲酯（MS）也很自然地出现，并且由于其较高的阈值限值（TLV）和残留状态低于最低残留限量（MRL），它们都被视为安全的熏蒸剂。评估了亚致死剂量的EF和MS，以确定熏蒸对小豆粒侵染小豆Call（Callosobruchus chinensis（L.））的生命阶段是否有协同作用。根据致死剂量（LD）值，中华绒螯蟹卵和成虫对EF敏感，其次是幼虫和p。成年人对MS最敏感，其次是卵和幼虫，而p是最能耐受的阶段。所有生命阶段的死亡率与单独的熏蒸处理总和相比，与亚致死剂量的EF和MS组合熏蒸处理的中华梭子蟹明显更高的协同作用。此外，通过协同熏蒸试验测试的最大剂量EF和MS不会阻碍小豆种子发芽的潜力。EF和MS之间的协同作用可以显着降低易燃EF对中华按蚊的剂量率，从而为EF + MS制剂作为保护储存的小豆的替代方法提供了良好的前景。