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Usefulness of serum galactomannan in initiating and modifying antifungal therapy in children with cancer and persistent high risk febrile neutropenia
Mycoses ( IF 4.9 ) Pub Date : 2020-05-28 , DOI: 10.1111/myc.13097
Matías Delgado-Araneda 1 , Romina Valenzuela 2 , Verónica de la Maza 2 , Marcela Rabello 2 , Ana M Álvarez 3, 4 , Verónica Contardo 4, 5 , Marcela Zubieta 4, 6 , Valentina Gutierrez 4, 7 , Ximena Claverie 4, 7 , Juan P Torres 2 , Carmen Salgado 4, 6 , Juan Tordecilla 4, 5 , Mónica Varas 3, 4 , Carmen L Avilés 4, 8 , Marcela Venegas 4, 8 , Milena Villarroel 2, 4 , María E Santolaya 2, 4
Affiliation  

Invasive fungal disease is a major cause of morbidity and mortality in children with cancer and high‐risk febrile neutropenia (HRFN). Repeated serum galactomannan (sGM) measurements have been described as an effective tool to guide therapy in adults under suspicion of invasive aspergillosis. However, the utility of this approach has not been reported in paediatric population.

中文翻译:

血清半乳甘露聚糖在癌症和持续高危发热性中性粒细胞减少症患儿启动和调整抗真菌治疗中的有用性

侵袭性真菌病是癌症和高危发热性中性粒细胞减少症 (HRFN) 儿童发病和死亡的主要原因。重复血清半乳甘露聚糖 (sGM) 测量已被描述为指导怀疑侵袭性曲霉病成人治疗的有效工具。然而,尚未报道这种方法在儿科人群中的效用。
更新日期:2020-05-28
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