During the first two decades of this century, conventional antimicrobial compounds have been found out to have more bacterial resistance. What has also been worrying is the rediscovery of the so-called "natural compounds", which in turn have a good name among the average citizen because of the former's plant or animal origin. However, they do not form a well-classified group of substances. This Special Issue consists of five reviews focusing on clinical bacteria applications in food and their specific effects upon virulent bacterial factors. You will also find a research on much needed, new antimicrobials sourced in extreme environments, and secondary metabolites of Burkholderia. This issue includes 12 original research papers which will provide you with an in-depth coverage of the protein extract activity, as well as the activity of other plant extracts, on fighting bacteria, fungi or diarrhea. Their use in broilers or laying eggs for production purposes has also been focused on in order to improve gut microbiota. Last but not least, we should not forget about honey and its effect; Allium sativum-fermented extracts, as well as other "natural" compounds, have been studied in their fight against biofilms. Furthermore, we have also examined the use of essential oils, which are currently used in edibles such as fresh sausages. The present work also deals with other applications such as natural compound derivatives as well as compound mixtures.

中文翻译：

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天然化合物作为抗菌剂。

在本世纪的前二十年中，发现传统的抗菌化合物具有更强的细菌抵抗力。人们还担心的是所谓的“天然化合物”的重新发现，由于前者的植物或动物起源，它们又在普通公民中享有盛名。但是，它们并未形成分类良好的物质组。本期特刊由五篇评论组成，重点讨论了食品中临床细菌的应用及其对强力细菌因素的特殊影响。您还将找到有关急需的，在极端环境中获得的新抗菌素以及伯克霍尔德氏菌次生代谢产物的研究。本期包括12篇原创研究论文，它们将为您深入介绍蛋白质提取物的活性，以及其他植物提取物对细菌，真菌或腹泻的抵抗力。为了改善肠道菌群，它们在肉鸡或产蛋中的生产也得到了关注。最后但并非最不重要的一点是，我们不应忘记蜂蜜及其功效。已经研究了大蒜发酵提取物以及其他“天然”化合物对抗生物膜的作用。此外，我们还研究了香精油的使用，香精油目前用于诸如新鲜香肠之类的食用食品中。本工作还涉及其他应用，例如天然化合物衍生物以及化合物混合物。我们不应忘记蜂蜜及其作用；已经研究了大蒜发酵提取物以及其他“天然”化合物对抗生物膜的作用。此外，我们还研究了香精油的使用，香精油目前用于诸如新鲜香肠之类的食用食品中。本工作还涉及其他应用，例如天然化合物衍生物以及化合物混合物。我们不应忘记蜂蜜及其作用；已经研究了大蒜发酵提取物以及其他“天然”化合物对抗生物膜的作用。此外，我们还研究了香精油的使用，香精油目前用于诸如新鲜香肠之类的食用食品中。本工作还涉及其他应用，例如天然化合物衍生物以及化合物混合物。