The disposable soma hypothesis explanation of the effects of caloric restriction (CR) on lifespan fails to explain why CR generates negative impacts alongside the positive effects and does not work in all species. I propose here a novel idea called the clean cupboards hypothesis which overcomes these problems.

中文翻译：

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为什么热量限制可以延长寿命和健康寿命？“干净的橱柜”假说

关于热量限制 (CR) 对寿命影响的一次性体细胞假说无法解释为什么 CR 在产生积极影响的同时也会产生负面影响，并且并非对所有物种都有效。我在这里提出了一个新的想法，称为“干净橱柜假说”，它克服了这些问题。