Chiral sulfinyl compounds, sulfoxides, sulfoximines, sulfinamides, and other derivatives, play an important role in asymmetric synthesis as versatile auxiliaries, ligands, and catalysts. They are also recognized as pharmacophores found in already marketed and well-sold drugs (e.g., esomeprazole) and used in drug design. This review is devoted to the modern methods of preparation of sulfinyl derivatives in enantiopure or enantiomerically enriched form. Selected new approaches leading to racemic products for which the asymmetric variant can be developed in the future are mentioned as well.

中文翻译：

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手性亚磺酰基化合物的现代立体选择性合成。

手性亚磺酰基化合物、亚砜、亚砜亚胺、亚磺酰胺和其他衍生物作为多功能助剂、配体和催化剂在不对称合成中发挥着重要作用。它们也被认为是已上市且畅销的药物（例如埃索美拉唑）中发现的药效团，并用于药物设计。本综述致力于对映体纯或对映体富集形式的亚磺酰基衍生物的现代制备方法。还提到了产生外消旋产物的选定新方法，将来可以开发不对称变体。