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Purgative/laxative actions of Globularia alypum aqueous extract on gastrointestinal-physiological function and against loperamide-induced constipation coupled to oxidative stress and inflammation in rats.
Neurogastroenterology & Motility ( IF 3.5 ) Pub Date : 2020-04-26 , DOI: 10.1111/nmo.13858
Najla Hajji 1 , Dalanda Wannes 1 , Mohamed-Amine Jabri 1 , Kais Rtibi 1 , Haifa Tounsi 2 , Afifa Abdellaoui 2 , Hichem Sebai 1
Affiliation  

Chronic constipation is a gastrointestinal functional disorder which affects patient quality of life. Therefore, many studies were oriented to search herbal laxative agents. In this study, we investigated the effect of Globularia alypum L. leaves aqueous extract (GAAE) against loperamide (LOP)‐produced constipation.

中文翻译:

球根水提取物对大鼠胃肠道生理功能和对抗洛哌丁胺引起的便秘的泻药/泻药作用与氧化应激和炎症的大鼠。

慢性便秘是一种胃肠功能障碍,会影响患者的生活质量。因此,许多研究旨在寻找草药泻药。在这项研究中,我们调查了球果叶水提取物(GAAE)对洛哌丁胺(LOP)产生的便秘的影响。
更新日期:2020-04-26
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