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Deep brain stimulation in dystonia: State of art and future directions.
Journal of Neuroscience Methods ( IF 3 ) Pub Date : 2020-04-25 , DOI: 10.1016/j.jneumeth.2020.108750
A Macerollo 1 , V Sajin 2 , M Bonello 1 , D Barghava 3 , S H Alusi 3 , P R Eldridge 3 , J Osman-Farah 3
Affiliation  

When considering Deep Brain Stimulation (DBS) surgical treatment of dystonia syndromes, it is important to consider multiple aspects of the disease and its presentation. It is crucial to know if the dystonia is idiopathic, inherited or acquired as well as focal, segmental or generalised. Careful phenotyping of idiopathic as well as inherited dystonias and accurate diagnosis of acquired dystonias informs the decision-making process for patients and clinicians by providing them with useful predictors of outcomes of the proposed surgery. Here, we provided a review of the current literature, highlighted the areas where evidence is scarce and suggested future directions for research.

中文翻译:

肌张力障碍中的深部脑刺激:技术发展水平和未来方向。

当考虑使用深度脑刺激(DBS)进行肌张力障碍综合征的外科治疗时,重要的是要考虑该疾病及其表现的多个方面。知道肌张力障碍是特发性,遗传性或获得性以及局灶性,节段性或泛发性至关重要。对特发性遗传性肌张力障碍和遗传性肌张力障碍的仔细表型分析,以及对获得性肌张力障碍的准确诊断,可以为患者和临床医生提供拟议手术结局的有用预测指标,从而为患者和临床医生提供决策依据。在这里,我们提供了对当前文献的回顾,重点介绍了证据稀缺的领域,并提出了未来的研究方向。
更新日期:2020-04-25
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