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Personalized Approach to Determination of Histidine-Rich Glycoprotein and E-Cadherin in Supernatants of Immunocompetent Blood Cells and Breast Biopsy Specimens in Breast Malignant and Non-Malignant Disease.
Doklady Biochemistry and Biophysics ( IF 0.8 ) Pub Date : 2020-04-27 , DOI: 10.1134/s1607672920010019 A I Autenshlyus 1, 2 , A V Bernado 1 , A A Studenikina 1 , A V Proskura 2 , K I Davletova 1 , I P Zhurakovskiy 1, 2 , S A Arkhipov 1, 2 , N A Varaksin 3 , S V Sidorov 4 , V V Lyakhovich 2
中文翻译:
个性化方法,用于测定在乳腺恶性和非恶性疾病中免疫活性血细胞上清液和乳腺活检标本中富含组氨酸的糖蛋白和E-钙黏着蛋白。
更新日期:2020-04-27
Doklady Biochemistry and Biophysics ( IF 0.8 ) Pub Date : 2020-04-27 , DOI: 10.1134/s1607672920010019 A I Autenshlyus 1, 2 , A V Bernado 1 , A A Studenikina 1 , A V Proskura 2 , K I Davletova 1 , I P Zhurakovskiy 1, 2 , S A Arkhipov 1, 2 , N A Varaksin 3 , S V Sidorov 4 , V V Lyakhovich 2
Affiliation
Abstract
The material of patients with invasive carcinoma of no special type (ICNT) and nonmalignant diseases (ND) of the mammary gland was studied. When comparing the concentrations of histidine-rich glycoprotein (HRG) and E-cadherin (CDH1), statistically significant differences between ICNT and ND by HRG in the supernatant of blood cells and its spontaneous production by biopsies and by CDH1 at its induced production, as well as by influence indices of polyclonal activators on the production of CDH1 were found. When comparing the expression of immunohistochemical markers, no statistically significant differences between ICNT and ND were obtained.中文翻译:
个性化方法,用于测定在乳腺恶性和非恶性疾病中免疫活性血细胞上清液和乳腺活检标本中富含组氨酸的糖蛋白和E-钙黏着蛋白。