Vacuum-assisted headspace solid-phase microextraction (Vac-HSSPME) is an emerging analytical technique, which further advances HSSPME by providing lower detection limits of analytes with poor volatility at shorter extraction times. This review discusses the theoretical aspects and possibilities of the Vac-HSSPME technique for analysis of environmental samples. Optimization of key parameters, currently available equipment and methods for quantification of organic pollutants in water and soil are considered. Key problems and limitations of the technique are discussed along with possible approaches for its future development. The technique has a well-developed theory, which could be used for modeling of the extraction process, faster method development, and optimization. Wider application of the technique is limited by the lack of automation, which, however, seems possible to develop and implement by manufacturers of commercial multi-purpose autosamplers for gas chromatography instruments. It has been shown that Vac-HSSPME allows decreasing cross-contamination of samples from the laboratory air, which is advantageous for identification and quantification of trace environmental pollutants. Simple equipment for the technique makes it possible to apply for on-site sample preparation and analysis of environmental samples.

真空辅助顶空固相微萃取（Vac-HSSPME）是一种新兴的分析技术，通过在较短的萃取时间内提供较低的挥发性差的分析物检测限，进一步提高了HSSPME。这篇评论讨论了Vac-HSSPME技术用于环境样品分析的理论方面和可能性。考虑了关键参数的优化，目前可用的定量水和土壤中有机污染物的设备和方法。讨论了该技术的关键问题和局限性以及未来发展的可能方法。该技术具有完善的理论，可用于提取过程的建模，更快的方法开发和优化。由于缺乏自动化，技术的广泛应用受到限制，但是，似乎有可能由气相色谱仪器的商用多功能自动进样器制造商开发和实施。已经表明，Vac-HSSPME可以减少实验室空气中样品的交叉污染，这对于鉴定和量化痕量环境污染物是有利的。该技术的简单设备使其可以应用于现场样品制备和环境样品分析。