Ultrafast magic angle spinning (MAS) technology and 1H detection have dramatically enhanced the sensitivity of solid-state NMR (ssNMR) spectroscopy of biopolymers. We previously showed that, when combined with polarization optimized experiments (POE), these advancements enable the simultaneous acquisition of multi-dimensional 1H- or 13C-detected experiments using a single receiver. Here, we propose a new sub-class within the POE family, namely HC-DUMAS, HC-MEIOSIS, and HC-MAeSTOSO, that utilize dual receiver technology for the simultaneous detection of 1H and 13C nuclei. We also expand this approach to record 1H-, 13C-, and 15N-detected homonuclear 2D spectra simultaneously using three independent receivers. The combination of POE and multi-receiver technology will further shorten the total experimental time of ssNMR experiments for biological solids.

中文翻译：

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使用极化优化实验（POE）在超快幻角旋转中进行多接收器固态NMR。

超快魔术角旋转（MAS）技术和1H检测技术大大提高了生物聚合物的固态NMR（ssNMR）光谱的灵敏度。我们以前的研究表明，与极化优化实验（POE）结合使用时，这些进步可以使用单个接收器同时采集多维1H或13C检测的实验。在这里，我们提出了POE家族中的一个新子类，即HC-DUMAS，HC-MEIOSIS和HC-MAeSTOSO，它们利用双接收器技术同时检测1H和13C核。我们还扩展了此方法，以使用三个独立的接收器同时记录1H，13C和15N检测到的同核2D光谱。