A mild and efficient nucleophilic monofluoromethylation of α-amido sulfones with trifluoromethyl α-fluorinated arylsulfonyl gem-diols as new building blocks has been developed, which affords N-Boc monofluoromethyl aryl sulfones in good yields with appropriate 5:1 diastereomeric ratio.

中文翻译：

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施工Ñ -Boc单氟芳基砜通过曼尼希反应α酰氨基砜与三氟甲基α氟化芳基磺酰基宝石-diols

已经开发出温和有效的α-酰胺基砜亲核单氟甲基化与三氟甲基α-氟化的芳基磺酰基宝石二醇作为新的结构单元，它可以以适当的5：1非对映体比率以良好的收率提供N-Boc单氟甲基芳基砜。