Our view of heredity can potentially be distorted by the ease of introducing heritable changes in the replicating gene sequences but not in the cycling assembly of regulators around gene sequences. Here, key experiments that have informed the understanding of heredity are reinterpreted to highlight this distortion and the possible variety of heritable changes are considered. Unlike heritable genetic changes, which are always associated with mutations in gene sequence, heritable epigenetic changes can be associated with physical or chemical changes in molecules or only changes in the system. The transmission of cycling stores along the continuous lineage of cells that connects successive generations creates waves of activity and localization of the molecules that together form the cell code for development in each generation. As a result, heritable epigenetic changes can include any that can alter a wave such as changes in form, midline, frequency, amplitude, or phase. Testing this integrated view of all heritable information will require the concerted application of multiple experimental approaches across generations.

中文翻译：

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可遗传的表观遗传变化改变了由循环信息存储维持的跨代波形。

我们对遗传的看法可能会因在复制基因序列中引入可遗传变化的容易程度而被扭曲，但在基因序列周围调节因子的循环组装中则不然。在这里，对理解遗传的关键实验进行了重新解释，以突出这种扭曲，并考虑了可能的各种遗传变化。与总是与基因序列突变相关的可遗传基因变化不同，可遗传的表观遗传变化可以与分子的物理或化学变化或仅与系统的变化相关。循环存储沿着连接连续几代的细胞的连续谱系的传输产生了分子的活动和定位波，这些分子共同形成了每一代发育的细胞代码。因此，可遗传的表观遗传变化可以包括任何可以改变波的变化，例如形式、中线、频率、幅度或相位的变化。测试所有可遗传信息的这种综合视图将需要跨代协同应用多种实验方法。