Phytochemistry Letters ( IF 1.7 ) Pub Date : 2020-04-22 , DOI: 10.1016/j.phytol.2020.04.001 Can Yang , Zhi Wang , Yan Qiu , Haiyan Zha , Xuedong Yang
One new hemiterpene glycoside, securiterpenoside G (1), one new furolactone-type lignan glycoside, (7R,8R,8′S)-glaberide I 4-O-β-D-glucopyranosyl-(1‴→4″)-O-β-D-glucopyranoside (2), along with two known lignan glycosides, (7R,8R,8′S)-glaberide I 4-O-β-D-glucopyranoside (3) and (7S,7′S,8R,8′R)-4,4′-dihydroxy-3,5,3′,5′tetramethoxy-7,9′:7′,9-diepoxylignane-4-O-β-D-glucopyranosyl-(1→4)-O-β-D-glucopyranoside (4) were isolated from the roots of Securidaca inappendiculata Hassk. The elucidation of their structures was based on the information of 1D, 2D NMR, HRESIMS, ECD, and the comparisons to published data. In addition, compounds 1 and 2 were evaluated for the anti-inflammatory activity against NO induced models.
中文翻译:
附生植物Securidaca inappendiculata Hassk的新型半萜烯和呋内酯型木脂素苷
一种新的半萜烯糖苷,securiterpenoside G(1),一种新的呋内酯型木脂体糖苷(7 R,8 R,8 'S)-glaberide I 4- O - β -D-吡喃葡萄糖基-(1‴→4″) - ø - β -D-吡喃葡糖苷(2),具有两个木脂素甙已知沿,(7 - [R,8 - [R,8'小号)-glaberide我4- ø - β -D-吡喃葡糖苷(3)和(7小号, 7 ′S,8 R,8′R)-4,4'-二羟基3,5,3',5'tetramethoxy -7,9-':7',9-diepoxylignane -4- ø - β -D-吡喃葡萄糖基- (1→4) - ø - β -D-吡喃葡萄糖苷(4)是从无齿草(Securidaca inappendiculata Hassk )的根中分离得到的。对它们的结构的阐明是基于1D,2D NMR,HRESIMS,ECD以及与已发表数据的比较。另外,评价化合物1和2对NO诱导的模型的抗炎活性。