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Development and validation of a liquid chromatography/tandem mass spectrometry method to quantify metabolites of phthalates, including di-2-ethylhexyl terephthalate (DEHTP) and bisphenol A, in human urine.
Rapid Communications in Mass Spectrometry ( IF 2 ) Pub Date : 2020-05-04 , DOI: 10.1002/rcm.8796
Gianfranco Frigerio 1 , Laura Campo 2 , Rosa Mercadante 1 , Patricia Martín Santos 3 , Pasquale Missineo 2 , Elisa Polledri 1 , Silvia Fustinoni 1, 2
Affiliation  

Several phthalates and bisphenol A are endocrine‐disrupting chemicals (EDCs). Recently, their use has been partially restricted and less toxic compounds, such as di‐2‐ethylhexyl terephthalate (DEHTP), have been placed on the market. The aim of this work was to develop and validate a method for the simultaneous quantitation of bisphenol A and urinary metabolites of phthalates, including DEHTP.

中文翻译:

开发和验证液相色谱/串联质谱法定量人类尿液中邻苯二甲酸酯的代谢物,包括对苯二甲酸二-2-乙基己酯(DEHTP)和双酚A。

几种邻苯二甲酸盐和双酚A是破坏内分泌的化学物质(EDC)。最近,它们的使用受到了部分限制,毒性较小的化合物,例如对苯二甲酸二-2-乙基己酯(DEHTP),已投放市场。这项工作的目的是开发和验证一种同时定量双酚A和邻苯二甲酸酯(包括DEHTP)的尿液代谢产物的方法。
更新日期:2020-05-04
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