The new bioanalysis systems development is an important step to the quality of people life improving. A significant number of novel bioanalytical methods bases on quantum dots photoluminescent signal detection and determination. A separate class of that kind of analytical system is enzyme-based luminescent assays, in which the value of quantum dots photoluminescence change by the product of the enzymatic reaction is used for the analyte concentration determination. The advantageous attributes of the photoluminescence quenching based systems are the simple equipment requirements, inexpensiveness, availability to use by the non-professionals and using an only dilution of the samples before analysis without any other pretreatment. Described bioanalytical systems are applicable in health care, food analysis and agriculture for a large number of objects. The key aim of the review is to compile the shortcomings and disadvantages of the published detection systems preventing their commercial application and searching the possible solutions.

新的生物分析系统的开发是改善人们生活质量的重要一步。大量新颖的生物分析方法都基于量子点的光致发光信号检测和确定。这类分析系统的另一类是基于酶的发光分析，其中，通过酶促反应产物产生的量子点光致发光变化值用于分析物浓度测定。基于光致发光猝灭的系统的有利属性是简单的设备要求，廉价，非专业人员可以使用的可用性，以及在分析前仅稀释样品而无需任何其他预处理的情况。所述的生物分析系统适用于医疗保健，食品分析和农业中的大量对象。审查的主要目的是要汇编已发布的检测系统的缺点和缺点，以防止其商业应用并寻找可能的解决方案。