The synthesis of a new group of triterpenoid acylates has been conducted on the basis of oleanolic, glycyrrhetic, and ursolic acids and betulin. 28-ortho-Methoxycynnamoylbetulin has been demonstrated to possess high activity against the influenza type A (H1N1) virus with the selectivity index SI > 100 while studying the activity of the synthesized compounds in relation to the reproduction of viral pathogens of respiratory infections. The high activity of 3,28-dinicotinoylbetulin against the papilloma virus (strain HPV-11) was detected with the selectivity index SI 35.

中文翻译：

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三萜酰化物的合成：甲型H1N1流感和乳头状瘤病毒的有效繁殖抑制剂

以齐墩果酸、甘草次酸、熊果酸和桦木脑为基础合成了一组新的三萜酰化物。在研究合成化合物与呼吸道感染病毒病原体繁殖相关的活性时，28-ortho-Methoxycynnamoylbetulin 已被证明对甲型流感 (H1N1) 病毒具有高活性，选择性指数 SI > 100。3,28-二烟酰桦木素对乳头状瘤病毒（HPV-11 株）具有高活性，选择性指数 SI 35。