The Cancer Journal ( IF 2.2 ) Pub Date : 2020-03-01 , DOI: 10.1097/ppo.0000000000000435 Meghan Bell 1 , Evrim B Turkbey 2 , Freddy E Escorcia 1
Ultrasound, computed tomography, magnetic resonance imaging, and [18F]F-fluorodeoxyglucose positron emission tomography are invaluable in the clinical evaluation of human cancers. Radiomics and radiogenomics tools may allow clinicians to standardize interpretation of these conventional imaging modalities, while better linking radiographic hallmarks to disease biology and prognosis. These advances, coupled with next-generation positron emission tomography imaging tracers capable of providing biologically relevant tumor information, may further expand the tools available in our armamentarium against human cancers. We present current imaging methods and explore emerging research that may improve diagnosis and monitoring of local, oligometastatic, and disseminated cancers exhibiting heterogeneous uptake of [18F]F-fluorodeoxyglucose, using hepatocellular carcinoma as an example.
中文翻译:
放射学,放射基因组学和下一代分子成像技术可增强肝细胞癌的诊断。
超声,计算机断层扫描,磁共振成像和[ 18 F] F-氟脱氧葡萄糖正电子发射断层扫描在人类癌症的临床评估中具有不可估量的价值。放射学和放射基因组学这些工具可以使临床医生标准化对这些常规成像方式的解释,同时更好地将放射线标记与疾病生物学和预后联系起来。这些进展,再加上能够提供生物学相关肿瘤信息的下一代正电子发射断层成像成像示踪剂,可能会进一步扩展我们的抗人类癌症武器库中可用的工具。我们当前的电流的成像方法和探索新的研究,其可以改进诊断和监测的地方,oligometastatic,和弥散性癌症表现出[异构摄取18 F] F-氟脱氧葡萄糖,使用肝细胞癌,例如,