Introduction: This review analyzes the efficacy of pneumococcal vaccinations in lung transplant patients before and after transplantation.Areas covered: This review addresses the risk for respiratory infections, in particular pneumococcal infections, in lung transplantation patients in the context of immunodeficiency and immunosuppressive medication. Vaccination is recommended to counteract the increased risk of pneumococcal infection, and the relevant guidelines are discussed in this review. The design of specific vaccination schedules is required because of the impaired antibody response in specific patient categories.Expert opinion: Lung transplantation candidates should be vaccinated with pneumococcal vaccines prior to transplantation. Currently, the 23-valent pneumococcal polysaccharide vaccine offers the broadest coverage, but the antibody response should be monitored. New generation pneumococcal conjugate vaccines with equally broad serotype coverage could be used in the future. During the post-transplantation period, the immune status of the patients should be monitored regularly, and vaccination should be repeated when indicated.

中文翻译：

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肺移植患者的肺炎球菌疫苗接种。

简介：这篇综述分析了肺移植患者在肺移植之前和之后的肺炎球菌疫苗接种的有效性。涵盖的领域：这篇综述针对免疫缺陷和免疫抑制药物治疗肺移植患者的呼吸道感染风险，特别是肺炎球菌感染。建议接种疫苗以抵消增加的肺炎球菌感染风险，本指南讨论了相关指南。由于特定患者类别的抗体反应受损，因此需要设计特定的疫苗接种时间表。专家意见：肺移植候选对象应在移植前接种肺炎球菌疫苗。目前，这种23价的肺炎球菌多糖疫苗覆盖面最广，但应监测抗体反应。将来可以使用具有相同血清型覆盖率的新一代肺炎球菌结合疫苗。在移植后的期间，应定期监测患者的免疫状况，并应在指示时重复接种疫苗。