当前位置: X-MOL 学术Hum. Immunol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 271 Southeast Asia Indians from Peninsular Malaysia.
Human Immunology ( IF 2.7 ) Pub Date : 2020-04-18 , DOI: 10.1016/j.humimm.2020.04.004
Ahmad Fauzi Nurul-Aain 1 , Lay-Kim Tan 1 , Hussein Heselynn 2 , Shahril Nor-Shuhaila 2 , Mageswaran Eashwary 2 , Sulaiman Wahinuddin 3 , Ing Soo Lau 4 , Suk Chyn Gun 5 , Mohamed-Said Mohd-Shahrir 6 , Mohd-Mokhtar Ainon 7 , Rosman Azmillah 4 , Othman Muhaini 8 , Murad Shahnaz 1 , Chun-Lai Too 9
Affiliation  

A total of 271 Southeast Asia Indians from Peninsular Malaysia were genotyped for HLA-A, -B, -C, -DRB1, and -DQB1 loci using polymerase chain reaction sequence-specific oligonucleotide probe hybridization methods. In this report, HLA-B and HLA-DQB1 was in Hardy-Weinberg proportions (HWEP) (p > 0.05). We observed significant deviation from the HWEP for HLA-A (p < 0.05), HLA-C (p < 0.01) and HLA-DRB1 (p < 0.01) loci. This genotype data is available in Allele Frequencies Network Database (AFND) Dos Santos et al. (2016).

中文翻译:

马来西亚半岛271名东南亚印第安人中的HLA-A,-B,-C,-DRB1和-DQB1等位基因和单倍型。

使用聚合酶链反应序列特异性寡核苷酸探针杂交方法对来自马来西亚半岛的271位东南亚印度人进行了HLA-A,-B,-C,-DRB1和-DQB1位点基因分型。在本报告中,HLA-B和HLA-DQB1处于Hardy-Weinberg比例(HWEP)(p> 0.05)。我们观察到HLA-A(p <0.05),HLA-C(p <0.01)和HLA-DRB1(p <0.01)位点的HWEP显着偏离。该基因型数据可从等位基因频率网络数据库(AFND)Dos Santos等获得。(2016)。
更新日期:2020-04-18
down
wechat
bug