Abstract

Ni doped CuO Nps (Ni_0.1CuO-GA) grown in gum acacia (GA) medium behaved as an efficient antibacterial material. The antibacterial activity of Ni_0.1CuO-GA was much higher than the control antibiotic (Amplicillin) and simple Ni doped CuO Nps. Different concentrations of GA were used (as the growth medium) to tune the material’s bioactivity. Among the synthesized Ni_0.1CuO-GA samples (G₁–G₄), G₃ sample (synthesized using 1.5% (w/v) GA) showed optimum antibacterial activity. The corresponding undoped sample (CuO-GA) was less active. The structural, morphological, compositional and optical properties of G₃ have been determined by FTIR, XRD, FESEM, HR-TEM and UV–visible analyses. It exhibited excellent antibacterial activity for Enterobacter, Klebsiella pneumoniae, Pseudomonas aeruginosa and Staphylococcus aureus bacterial strains (ZOI being 27 mm, 28.75 mm, 27.50 mm and 26.50 mm respectively). ZOI for the reference antibiotic for respective bacterial strains were 17.50 mm, 18.50 mm, 18.25 mm and 19.50 mm respectively, while ZOI for neat CuO Nps, G₁, G₂, G₄ and CuO-GA samples ranged between 21 and 24 mm for the same doses. The advantage Ni doping combined with the usage of GA as growth medium is evident by the excellent antibacterial behaviour of G₃.

中文翻译：

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胶相思改性的Ni掺杂的CuO纳米粒子：一种出色的抗菌材料。

摘要

在胶合欢（GA）培养基中生长的掺Ni的CuO Nps（Ni _0.1 CuO-GA）表现为一种有效的抗菌材料。Ni _0.1 CuO-GA的抗菌活性远高于对照抗生素（氨苄青霉素）和简单的Ni掺杂CuO Nps。使用不同浓度的GA（作为生长培养基）来调节材料的生物活性。在合成的Ni _0.1 CuO-GA样品（G ₁ –G ₄）中，G ₃样品（使用1.5％（w / v）GA合成）显示出最佳的抗菌活性。相应的未掺杂样品（CuO-GA）的活性较低。G ₃的结构，形态，组成和光学性质已通过FTIR，XRD，FESEM，HR-TEM和UV可见分析确定。它对肠杆菌，肺炎克雷伯菌，铜绿假单胞菌和金黄色葡萄球菌细菌菌株（ZOI分别为27 mm，28.75 mm，27.50 mm和26.50 mm）表现出优异的抗菌活性。相应细菌菌株的参考抗生素的ZOI分别为17.50 mm，18.50 mm，18.25 mm和19.50 mm，而纯CuO Nps，G ₁，G ₂，G ₄和CuO-GA样品的ZOI在21至24 mm之间。相同剂量 Ni掺杂结合GA用作生长培养基的优势通过G ₃的优异抗菌性能得以证明。