The effect of fluid flow on tissue adaptation was the focus of many research works during the last years. Moreover, the use of poroelasticity models to simulate and understand the interstitial flow movement has taken interest due to the possibility to include the fluid effect on mechanical simulations. In particular, shear stresses induced by bone canalicular fluid flow are suggested to be one of the mechanical stimulus controlling bone remodeling processes. Due to the high difficulty to measure canalicular fluid flow and shear stresses, computational poroelastic models can be used in order to estimate these parameters. In this work, a finite element dual porosity model based on Russian doll poroelasticity is developed. Two experiments with a turkey ulna and a human femur are simulated. Bone lacuno-canalicular fluid flow is computed and compared with the experimental results, focusing on the zones of bone remodeling and showing a relation between this flow and the bone formation process.

近年来，流体流动对组织适应的影响是许多研究工作的重点。此外，由于可以将流体效应包括在力学模拟中，因此使用孔隙弹性模型来模拟和理解间隙流动运动引起了人们的兴趣。特别地，由骨小管流体流动引起的剪切应力被认为是控制骨重塑过程的机械刺激之一。由于很难测量导管流体的流量和切应力，因此可以使用计算多孔弹性模型来估算这些参数。在这项工作中，建立了基于俄罗斯娃娃孔隙弹性的有限元双重孔隙度模型。模拟了火鸡尺骨和人股骨的两个实验。