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A review of the potential genes implicated in follicular atresia in teleost fish
Marine Genomics ( IF 1.9 ) Pub Date : 2019-09-08 , DOI: 10.1016/j.margen.2019.100704
Paola González-Kother , Marcelo E. Oliva , Arnaud Tanguy , Dario Moraga

In recent years, numerous studies conducted on teleost fish have highlighted the contribution of transcriptomic studies in elucidating the physiological mechanisms underlying the molecular events of oogenesis and follicular atresia, enabling the identification of potential genes and molecular networks that participate in both the reproductive cycle and the process of follicular atresia. Atresia can affect the reproductive potential of females by reducing the healthy eggs that a female can spawn in both aquaculture and wild populations. The substantial diversity of reproductive strategies exhibited by teleost fish has contributed to the difficulty in identifying common genes between species, but a set of core genes has emerged as potential markers for atresia in relation to apoptosis/autophagy, lipid metabolism, oxidative metabolism and other physiological processes similar to those identified in other vertebrates, even mammals. We review the current status of the genes that have been identified in ovaries with atretic oocytes. Our primary goal is to review the current status regarding gene expression during gonadal development and follicular atresia. This information will enable us to understand the factors and expression patterns involved in the follicular atresia of teleost fish.



中文翻译:

硬骨鱼卵泡闭锁的潜在基因综述

近年来,对硬骨鱼的大量研究强调了转录组学研究在阐明卵子发生和卵泡闭锁的分子事件的生理机制方面的贡献,从而能够鉴定参与生殖周期和卵子发育的潜在基因和分子网络。滤泡闭锁的过程。闭锁可以通过减少雌性在水产养殖和野生种群中产生的健康卵来影响雌性的繁殖潜力。硬骨鱼表现出的大量繁殖策略导致难以识别物种之间的共同基因,但一组核心基因已成为与细胞凋亡/自噬,脂质代谢,氧化代谢和其他生理过程类似于在其他脊椎动物,甚至哺乳动物中发现的过程。我们审查了卵巢卵母细胞中已鉴定的基因的当前状态。我们的主要目标是回顾性腺发育和滤泡性闭锁期间基因表达的当前状态。这些信息将使我们能够了解硬骨鱼卵泡闭锁的因素和表达方式。

更新日期:2019-09-08
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