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A mean first passage time genome rearrangement distance.
Journal of Mathematical Biology ( IF 1.9 ) Pub Date : 2020-04-06 , DOI: 10.1007/s00285-020-01487-w
Andrew R Francis 1 , Henry P Wynn 2
Affiliation  

This paper introduces a new way to define a genome rearrangement distance, using the concept of mean first passage time from probability theory. Crucially, this distance provides a genuine metric on genome space. We develop the theory and introduce a link to a graph-based zeta function. The approach is very general and can be applied to a wide variety of group-theoretic models of genome evolution.

中文翻译:

平均第一次通过时间基因组重排距离。

本文介绍了一种使用概率论中的平均首次通过时间的概念来定义基因组重排距离的新方法。至关重要的是,该距离为基因组空间提供了真正的衡量标准。我们发展了这一理论,并介绍了到基于图的zeta函数的链接。该方法非常通用,可以应用于多种基因组进化的群体理论模型。
更新日期:2020-04-16
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