Age-related macular degeneration as one of the most common causes of worldwide vision loss needs a proper approach for treatment. Therein, cell therapy and regenerative medicine can hold a great promise to be an effective approach. Accordingly, some preclinical and clinical studies were conducted to search around the therapeutic influence of stem cells in Age-related macular degeneration models and subjects. Hereupon, the purpose of the current review is to discuss the mechanisms of age-related macular degeneration, appropriate animal models along with suitable dosage and route of stem cell administration for its treatment.

中文翻译：

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基于细胞的方法治疗与年龄有关的黄斑变性。

与年龄有关的黄斑变性是全球视力丧失的最常见原因之一，需要采取适当的治疗方法。其中，细胞疗法和再生医学有望成为一种有效的方法。因此，进行了一些临床前和临床研究以寻找干细胞在与年龄有关的黄斑变性模型和受试者中的治疗作用。因此，本综述的目的是讨论与年龄有关的黄斑变性的机制，合适的动物模型以及治疗干细胞的合适剂量和途径。