ABSTRACT Four compounds containing two lactate groups and one perfluorocarbon chain are designed and synthesised, whose chirality is tuned by changing the chirality of the lactic acid residues. (R,S)- and (S,R)-2 stereoiosomers exhibit an enantiotropic SmA phase, while (R,R)- and (S,S)-2 stereoisomers exhibit an enantiotropic SmA phase and an enantiotropic SmCd* one. Therefore, the chirality of the compounds plays an important role in the mesomorphic behaviours of the compounds. The optical activity of these liquid crystals is dominated by the chirality of the lactate group near the core. (R)- and (S)-1 with one lactic acid residue and one perfluorocarbon chain exhibit only an enantiotropic SmA phase. Graphical Abstract

中文翻译：

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手性驱动的介晶行为差异：含有两个乳酸基团的二手性化合物

摘要 设计并合成了四种含有两个乳酸基团和一个全氟化碳链的化合物，通过改变乳酸残基的手性来调节其手性。(R,S)- 和 (S,R)-2 立体异构体表现出对映 SmA 相，而 (R,R)- 和 (S,S)-2 立体异构体表现出对映 SmA 相和对映 SmCd* 相。因此，化合物的手性在化合物的介晶行为中起着重要作用。这些液晶的旋光性受核心附近乳酸基团的手性支配。(R)- 和 (S)-1 具有一个乳酸残基和一个全氟化碳链，仅表现出对映性 SmA 相。图形概要