Bacteria are known to communicate with each other through signalling molecules that regulate gene expression within the population. However, the way in which hydrophobic signals are released and transmitted among bacterial population is not well understood. Recent studies show that membrane vesicles (MVs) are involved in delivering hydrophobic signals, such as in N‐hexadecanoyl‐l‐homoserine lactone (C16‐HSL) signalling in Paracoccus denitrificans Pd1222. In this study, we identified the AHLs produced in Paracoccus aminophilus JCM7686, Paracoccus aminovorans NBRC16711, Paracoccus thiocyanatus JCM20756, Paracoccus versutus JCM20754 and Paracoccus yeei ATCC BAA‐599, and show that the main AHL produced in all the strains is C16‐HSL. Our results show that these Paracoccus species also release MVs that carry C16‐HSL, but at different proportions. Most of the strains carry C16‐HSL in MVs, while in P. aminophilus JCM7686, very little C16‐HSL was detected in MVs, but was found in other fractions of the supernatant. Given the utilization of a common signal, we showed that these Paracoccus species can share signals with P. denitrificans Pd1222, and examined the role of MVs in signalling. Our study provides new insights into the way in which bacteria communicate using hydrophobic signals.

中文翻译：

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膜囊泡参与副球菌物种的长链AHL传递。

已知细菌通过调节种群内基因表达的信号分子相互通讯。但是，疏水信号在细菌种群之间的释放和传播方式尚不清楚。最近的研究表明，膜囊泡（MVs）参与传递疏水信号，例如反硝化副球菌Pd1222中的N-十六烷酰基-1-高丝氨酸内酯（C16-HSL）信号。在这项研究中，我们鉴定出了氨基嗜热副球菌JCM7686，氨基嗜热副球菌NBRC16711，硫氰酸副球菌JCM20756 ，副对球菌JCM20754和yeara副球菌ATCC BAA-599，表明所有菌株中产生的主要AHL是C16-HSL。我们的结果表明，这些副球菌也释放携带C16-HSL的MV，但比例不同。大多数菌株在MVs中携带C16-HSL，而在嗜P.aminophilus JCM7686中，在MVs中检测到极少的C16-HSL，但在上清液的其他部分中发现。给定一个共同的信号的使用，我们发现，这些副球菌与物种可以分享信号P.脱氮Pd1222，并检查信令MV的作用。我们的研究为细菌利用疏水信号交流的方式提供了新的见解。