Relationship of sputum mast cells with clinical and inflammatory characteristics of asthma,Clinical & Experimental Allergy

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Relationship of sputum mast cells with clinical and inflammatory characteristics of asthma
Clinical & Experimental Allergy ( IF 6.1 ) Pub Date : 2020-05-04 , DOI: 10.1111/cea.13609
Michael Fricker _{1,

2,

3} , Ling Qin ₁ , Natalie Niessen _{1,

2,

3} , Katherine J Baines _{1,

3} , Vanessa M McDonald _{1,

2,

3,

4} , Hayley A Scott _{1,

3} , Jodie L Simpson _{1,

3,

4} , Peter G Gibson _{1,

2,

3,

4}

Affiliation

Mast cells (MCs) are innate immune cells that regulate atopic and non‐atopic inflammation in the airways. MCs play a critical role in the pathogenesis of asthma, yet their relationship to airway and systemic inflammation and clinical characteristics of asthma is poorly understood.

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