The innate immune system is the first‐line defence against invading pathogens, and the main molecules involved in recognizing invading pathogens are the pattern recognition receptors. Accumulating evidences have demonstrated that activation and termination of the immune responses are regulated by various layers of regulators and mechanisms. MicroRNAs (miRNAs) are a group of small non‐coding RNAs that emerged as critical component of the complex regulatory networks in fish immune responses. In this review, we have summarized miRNA regulation in teleost fish, which can provide new insights into the regulation of innate immune receptor pathways in fish. Meanwhile, we comprehensively discuss the recent researches on how teleost miRNAs respond to the signalling pathways of innate immune receptors, including Toll‐like receptors, retinoic acid‐inducible gene‐I‐like receptors and Nod‐like receptors.

中文翻译：

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硬骨鱼中Toll样受体，RIG-I样受体和Nod样受体途径的MicroRNA调控

天生的免疫系统是抵御入侵病原体的第一线防御，识别入侵病原体的主要分子是模式识别受体。越来越多的证据表明，免疫反应的激活和终止受各种调节剂和机制的调节。微小RNA（miRNA）是一组小的非编码RNA，它们已成为鱼类免疫应答中复杂调控网络的关键组成部分。在这篇综述中，我们总结了硬骨鱼中的miRNA调控，可以为鱼类中先天免疫受体途径的调控提供新的见解。同时，我们全面讨论了最近的研究，关于硬骨鱼miRNA如何响应先天性免疫受体（包括Toll样受体）的信号传导途径，